Heather Bedard, C.H.E.
Methylsulfonylmethane is a chemical that is naturally made by the body and scientists are unsure how supplementing with it can have an effect on the body as supplementation isn’t generally needed. Methylsulfonylmethane can be found naturally in many different fruits and vegetables and this way of ingesting it is most likely the best way of utilizing its anti-cancer properties.
Studies in vivo and in vitro have shown Methylsulfonylmethane’s ability to inhibit cell proliferation and replication as well as apoptosis as shown in this study titled, “Methylsulfonylmethane Induces G1 Arrest and Mitochondrial Apoptosis in YD 38 Gingival Cancer Cells”.[1] This study was done on gingival squamous adenocarcinoma, a rare cancer. Other studies on methylsulfonylmethane include breast cancer[2] and bladder cancer[3]. While I couldn’t find any human studies, the mechanism of action seems to be very clear in vitro.
Because of the lack of human studies, it is difficult to say what the success rate would be and the effectiveness in real life situations. I find this option to be very intriguing and would possibly consider it depending on how the research progresses. I don’t think it would be wise to recommend it based on the available research and lack of data. However, it may be an option for an individual to talk with their doctor about depending on the situation.
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[1] NIPIN S P, DONG YOUNG KANG, BAEK JOONG KIM, YOUN HEE JOUNG, PRAMOD DARVIN, HYO JOO BYUN, JOONG GON KIM, JE UK PARK and YOUNG MOK YANG
Anticancer Research April 2017, 37 (4) 1637-1646;
[2] Lim EJ, Hong DY, Park JH, Joung YH, Darvin P, Kim SY, Na YM, Hwang TS, Ye SK, Moon ES, Cho BW, Do Park K, Lee HK, Park T, Yang YM
PLoS One. 2012; 7(4):e33361
[3] Joung YH, Na YM, Yoo YB, Darvin P, Sp N, Kang DY, Kim SY, Kim HS, Choi YH, Lee HK, Park KD, Cho BW, Kim HS, Park JH, Yang YM
Int J Oncol. 2014 Mar; 44(3):883-95